This is not unexpected but it looks like there will be LEGO Marvel Super Heroes Avengers: Infinity War sets coming next year to coincide with the movie premiering in theaters. LEGO has been releasing sets for every movie from the Marvel Cinematic Universe starting with The Avengers up to Thor: Ragnarok which comes out in a few months. The only movie that didn’t have a LEGO set tie-in was Thor: The Dark World.
It’ll be interesting to see if Thanos will be a regular minifigure or if he’ll use the same mold as in the Avenjet Space Mission (76049) but recolored. I have a feeling it’ll be the latter since LEGO already has the mold and usually larger characters use bigfigs instead of minifigures.